Category Archives: Vesicular Monoamine Transporters

1H NMR (400 MHz, CDCl3), characteristic peaks: 7.65C7.78 (br m, 1H), 7.27C7.40 (m, 5H), 6.93C7.02 (br m, 1H), 6.80 (ddd, = 12.6, 8.5, 2.6 Hz, 1H), 4.06 (dd, = 11.7, 2.2 Hz, 1H), 3.53 (dd, = 10.2, 3.7 Hz, 1H), 2.50C2.61 (br m, Ginsenoside Rh1 1H), 1.62 (ddd, = 14, 4, 2.5 Hz, 1H), 0.89 (d, = 6.6 Hz, 3H). 539.2 [M C H]+. 523.2 [M + H]+. one of the underlying causes of Alzheimers disease (AD), which is the most common reason for cognitive decline in the elderly.1 AD pathology is characterized by the presence of extracellular plaques in the hippocampal and cortical regions of the brain, accompanied by intraneuronal neurofibrillary tangles and extensive neuronal loss.2 A, the major protein constituent of amyloid plaques, is derived from sequential cleavage of the type I integral membrane protein, amyloid precursor protein (APP), by two proteases: BACE1 and -secretase.3 Proteolytic cleavage of…

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