Category Archives: UPS

´╗┐Supplementary Materials Supplemental material supp_90_20_9263__index. infection of various mammalian cell types. Exemplar reassortant viruses also replicated to similar titers in mice, although mice infected with viruses with the avian virus-derived segment 8s had reduced weight loss compared to that achieved in mice infected with the A/Puerto Rico/8/1934 (H1N1) parent. transmission were not significantly different. We conclude that while the introduction of an avian virus segment 8 into mammals is a relatively rare event, the dogma of the B allele being especially restricted is misleading, with implications in the assessment of the pandemic potential of avian influenza viruses. IMPORTANCE Influenza A virus (IAV) can adapt to poultry and mammalian species, inflicting AMG 548 a great socioeconomic load on health insurance and farming care and attention sectors. Host version most likely requires multiple viral factors. Here, we investigated the role of IAV segment 8. Segment 8 has evolved into two distinct clades:…

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